Study claims Ozempic & Wegovy may reduce risk of dementia. Call 571-259-9384 to discuss how Senior Home care services can provide care for your loved ones at home and keep them safe, and if you cant afford the care we can discuss how you can get care for FREE.
Previous studies showed that the medications known as GLP-1 agonists made by Danish pharma
giant Novo Nordisk improved the cognitive behaviour and pathological features in Alzheimer’s disease
patients and animals. This may be related to the improvement of glucose metabolism in the brain.
However, their mechanisms have not been clear.
To explore, a team from Shanxi Medical University, prescribed semaglutide, the active ingredient in the
drugs, to mice with mutations associated with Alzheimer’s.
The results showed that semaglutide, besides improving glucose metabolism in the brain, led to an
improvement in learning and memory. It also decreased in amyloid beta plaques and neurofibrillary
tangles — hallmark of Alzheimer’s disease.
“The study revealed that semaglutide reduces pathology of Alzheimer’s disease animals such as memory
impairment,” the researchers said in the paper published in the journal Neuropharmacology.
Even as semaglutide is currently in phase III clinical trials in Alzheimer’s patients, the study “adds
important information of how the drug protects neurons in the brain”, the researchers noted.
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